Élie Wollman

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Élie Wollman
Born (1917-07-04)July 4, 1917
Paris, France
Died June 1, 2008(2008-06-01) (aged 90)
Paris, France
Fields Microbial genetics
Institutions Pasteur Institute
Thesis 'Recherche sur la conjugaison des bactéries et sur le déterminisme génétique de la lysogénie (studies on bacterial conjugation and genetic determinism of lysogeny) (1958)
Known for Plasmids, conjugation
Spouse Odile Wollman

Élie Lèo Wollman (July 4, 1917 – June 1, 2008) was a French microbial geneticist who first described plasmids (what he termed "episomes"), and served as vice director of research for the Pasteur Institute for twenty years.[1] He was awarded the 1976 Grand Prix Charles-Leopold Mayer by the French Academy of Sciences and Chevalier of the French Legion of Honour.[1]

Research[edit]

  • In his lab at the Pasteur Institute in Paris Wollman played a key role in the elucidation of the organization of genetic material.[2]
  • Developed the experimental method of interrupted mating, which underpinned the gene mapping of bacterial chromosomes.[3][4] This work laid the foundation for Francois Jacob's Nobel prize-winning work.[1]
  • With Francois Jacob, he published a monograph, Sexuality and the genetics of bacteria (French title: La sexualité des bactéries), in 1959.[5]

Selected publications[edit]

  • Wollman, Élie L; François Jacob (1961). Sexuality and the genetics of bacteria. New York: Academic Press. 
  • Wollman, E. L.; Jacob, F.; Hayes, W. (1956). "Conjugation and Genetic Recombination in Escherichia coli K-12". Cold Spring Harbor Symposia on Quantitative Biology 21: 141–162. doi:10.1101/SQB.1956.021.01.012. PMID 13433587.  edit

References[edit]

  1. ^ a b c Dantzer, Robert; Keith W. Kelley (2009). "Wollman, Elie (1917–2008)". In National Academy of Sciences (U.S.). Biographical Memoirs. Washington, D.C.: National Academies Press. ISBN 978-0-309-09579-2. 
  2. ^ Archives Pasteur. "Elie Wollman (1917–2008) - Notice biographique" (Biographical sketch). Archives de l'Institut Pasteur. Retrieved 2012-12-24. 
  3. ^ Wollman, E. L.; Jacob, F.; Hayes, W. (1956). "Conjugation and Genetic Recombination in Escherichia coli K-12". Cold Spring Harbor Symposia on Quantitative Biology 21: 141–162. doi:10.1101/SQB.1956.021.01.012. PMID 13433587.  edit
  4. ^ Harré, Rom (2002). Great Scientific Experiments: Twenty Experiments That Changed Our View of the World. Courier Dover Publications. ISBN 978-0-486-42263-3. 
  5. ^ Wollman, Élie L; François Jacob (1961). Sexuality and the genetics of bacteria. New York: Academic Press.