(S)-carnitine 3-dehydrogenase

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(S)-carnitine 3-dehydrogenase
Identifiers
EC number 1.1.1.254
CAS number 169277-49-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a (S)-carnitine 3-dehydrogenase (EC 1.1.1.254) is an enzyme that catalyzes the chemical reaction

(S)-carnitine + NAD+ \rightleftharpoons 3-dehydrocarnitine + NADH + H+

Thus, the two substrates of this enzyme are (S)-carnitine and NAD+, whereas its 3 products are 3-dehydrocarnitine, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-carnitine:NAD+ oxidoreductase.

References[edit]

  • Setyahadi S, Ueyama T, Arimoto T, Mori N, Kitamoto Y (1997). "Purification and properties of a new enzyme, D-carnitine dehydrogenase, from Agrobacterium sp. 525a". Biosci. Biotechnol. Biochem. 61 (6): 1055–8. doi:10.1271/bbb.61.1055. PMID 9214773.