From Wikipedia, the free encyclopedia
Jump to: navigation, search
"R130" redirects here. For the road, see Route 130. For the subway car, see R110A (New York City Subway car).
1,1,2,2-Tetrachloroethane3D.png 1,1,2,2-tetrachloroethane3D2.png
CAS number 79-34-5 YesY
PubChem 6591
ChemSpider 6342 YesY
KEGG C19534 N
ChEBI CHEBI:36026 YesY
Jmol-3D images Image 1
Molecular formula C2H2Cl4
Molar mass 167.85 g mol−1
Appearance Clear liquid
Density 1.59 g/cm3
Melting point −44 °C (−47 °F; 229 K)
Boiling point 146.5 °C (295.7 °F; 419.6 K)
Solubility in water 1 g/350 mL
TWA 5 ppm (35 mg/m3) [skin]
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

1,1,2,2-Tetrachloroethane is a chlorinated derivative of ethane. It has the highest solvent power of any chlorinated hydrocarbon.[1] As a refrigerant, it is used under the name R-130.

It was once widely used as a solvent and as an intermediate in the industrial production of trichloroethylene, tetrachloroethylene, and 1,2-dichloroethylene.[2] However, 1,1,2,2-tetrachloroethane is no longer used much in the United States due to concerns about its toxicity.[3]

Chronic inhalation exposure in humans results in jaundice and an enlarged liver, headaches, tremors, dizziness, numbness, and drowsiness. The U.S. Environmental Protection Agency has classified it as a Group C possible human carcinogen.[3]

For occupational exposure limits, the Occupational Safety and Health Administration has set a permissible exposure limit for dermal exposures at 5 ppm over an eight-hour time-weighted average. The National Institute for Occupational Safety and Health has a more protective recommended exposure limit for dermal exposures at 1 ppm over an eight-hour time-weighted average.[4]

See also[edit]


  1. ^ a b Merck Index, 11th Edition, 9125.
  2. ^ Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for 1,1,2,2-Tetrachloroethane (Update). U.S. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1996.
  3. ^ a b Tetrachloroethane at U.S. EPA
  4. ^ CDC - NIOSH Pocket Guide to Chemical Hazards