1,2-Naphthoquinone

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1,2-Naphthoquinone
1,2-Naphthoquinone
Identifiers
CAS number 524-42-5 YesY
PubChem 10667
ChemSpider 10217 YesY
KEGG C14783 YesY
ChEMBL CHEMBL52347 YesY
Jmol-3D images Image 1
Properties
Molecular formula C10H6O2
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula C
10
H
6
O
2
.

This double ketone (quinone) is a reactive metabolite of naphthalene and is found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.[1]

See also[edit]

References[edit]

  1. ^ Qian, W.; Shichi, H. (2001). "Naphthoquinone-Induced Cataract in Mice: Possible Involvement of Ca2+ Release and Calpain Activation". Journal of Ocular Pharmacology and Therapeutics 17 (4): 383–392. doi:10.1089/108076801753162799. PMID 11572469. 

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