10-Deacetylbaccatin

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10-Deacetylbaccatin III
Deacetylbaccatin.png
10-Deacetylbaccatin III molecule
Identifiers
CAS number 32981-86-5 N
PubChem 154272
ChemSpider 135935 YesY
ChEBI CHEBI:18193 YesY
ChEMBL CHEMBL393912 YesY
Jmol-3D images Image 1
Properties
Molecular formula C29H36O10
Molar mass 544.59 g/mol
Appearance colorless solid
Melting point 234 °C (453 °F; 507 K)
Solubility in water insoluble
Solubility soluble in methanol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).

10-deacetylbaccatin III 10-O-acetyltransferase converts 10-Deacetylbaccatin to baccatin III. (acetyl-CoA + 10-deacetylbaccatin III \rightleftharpoons CoA + baccatin III)

External links[edit]