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|Centuries:||12th century – 13th century – 14th century|
|Decades:||1220s 1230s 1240s – 1250s – 1260s 1270s 1280s|
|Years:||1247 1248 1249 – 1250 – 1251 1252 1253|
|1250 by topic|
|State leaders – Sovereign states|
|Birth and death categories|
|Births – Deaths|
|Establishments and disestablishments categories|
|Establishments – Disestablishments|
|Art and literature|
|1250 in poetry|
|Ab urbe condita||2003|
|Bahá'í calendar||−594 – −593|
|English Regnal year||34 Hen. 3 – 35 Hen. 3|
|Chinese calendar||己酉年 (Earth Rooster)
3946 or 3886
— to —
庚戌年 (Metal Dog)
3947 or 3887
|- Vikram Samvat||1306–1307|
|- Shaka Samvat||1172–1173|
|- Kali Yuga||4351–4352|
|Japanese calendar||Kenchō 2
|Minguo calendar||662 before ROC
|Thai solar calendar||1793|
|Wikimedia Commons has media related to 1250.|
- The world population is estimated at between 400 and 416 million individuals.
- Very approximate transition from the Medieval Warm Period to the Little Ice Age.
- Medieval music: end of the Notre Dame school of polyphony
- February – After the death of Erik Eriksson on February 2, Valdemar I, who is the eldest son of Birger jarl, is elected king of Sweden and becomes the first Swedish king of the Folkung house.
- April 30 – King Louis IX of France is released by his Egyptian captors, after paying a ransom of one million dinars and turning over the city of Damietta.
- October 12 – A great storm shifts the mouth of the River Rother 12 miles (20 km) to the west; a battering series of strong storms significantly alter other coastal geography as well (see Romney Marsh).
- December 13 – Frederick II, Holy Roman Emperor, dies, beginning a 23-year-long interregnum known as the Great Interregnum. Frederick II is the last Holy Roman Emperor of the Hohenstaufen dynasty; after the interregnum, the empire passes to the Habsburgs.
- The Lombard League dissolves upon the death of its member states' nemesis, Frederick II, Holy Roman Emperor.
- King Afonso III of Portugal captures the Algarve from the Moors, thus completing the expulsion of the Moors from Portugal.
- Albertus Magnus isolates the element arsenic as the 8th discovered metal. He also first uses the word oriole to describe a type of bird (most likely the golden oriole).
- The University of Valladolid is founded in Spain.
- The Rialto Bridge in Venice, Italy is converted from a pontoon bridge to a permanent, raised wooden structure.
- Vincent of Beauvais completes his proto-encyclopedic work, The Greater Mirror.
- The Parlement law courts of ancien régime France are established.
- A plague breaks out in the city Naples (in present-day Italy), called the Naple's Plague.
- Villard de Honnecourt draws the first known image of a sawmill.
- A kurultai is called by Batu Khan in Siberia as part of maneuverings to eventually elect Möngke Khan as khan of the Mongol empire in 1251.
- Starting in this year and ending in 1275, the Muslim Shougeng Pu serves as the Commissioner of Merchant Shipping for the Song Dynasty Chinese seaport at Quanzhou due to his effort on defeating pirates, according to a monograph on the Chinese shipping industry and maritime economy in dynasties of Tang and Sung written by Jitsuzo Kuwabara (桑原騭藏, 1870-1931). Shougeng Pu is likely a Persian or Arabic Muslim.
- July 3 – Battle of Fariskur: Louis IX of France is captured by Baibars' Mamluk army while he is in Egypt conducting the Seventh Crusade; he later has to ransom himself.
- The Bahri dynasty of Mamluks seize power in Egypt.
- The Welayta state is founded in present-day Ethiopia.
- In Tunis, a popular rebellion against newly arrived, wealthy and influential Andalusian refugees breaks out and is violently put down.
- The Flemish town of Douai emits the first recorded redeemable annuities in medieval Europe, confirming a trend of consolidation of local public debt stated in 1218 in Rheims.
- The Sienese bankers belonging to the firm known as the Gran Tavola, under the steering of the Bonsignori brothers, become the main financiers of the Papacy. 
- Guido Cavalcanti, Italian poet (d. 1300)
- Dmitri of Pereslavl, Grand-duke of Vladimir-Suzdal (d. 1294)
- Pierre Dubois, French publicist (approximate date; d. c. 1312)
- Moses de Leon, compiler of the Zohar (approximate date; d. 1305)
- Giovanni Pisano, Italian sculptor (approximate date; d. 1314)
- Asher ben Yehiel, Jewish Talmudist (approximate date; d. 1328)
- September 17 – Robert II of Artois
- February 2 – Erik Eriksson, king of Sweden 1222–1229 and since 1234 (b. 1216)
- February 8
- April 6 – Guillaume de Sonnac, Grand Master of the Knights Templar
- June 18 – Teresa of Portugal
- August 9 – King Eric IV of Denmark (b. 1216)
- October 4 – Herman VI, Margrave of Baden
- December 13 – Frederick II, Holy Roman Emperor (b. 1194)
- Leonardo of Pisa, Italian mathematician
- Matej Ninoslav, Croatian ban
- Le Roy Ladurie, Emmanuel; Bray, Barbara (1971). Times of Feast, Times of Famine: a History of Climate Since the Year 1000. Garden City, NY: Doubleday. ISBN 0-374-52122-0. OCLC 164590.
- de Epalza, Miguel (1999). Negotiating cultures: bilingual surrender treaties in Muslim-Crusader Spain under James the Conqueror. Brill. p. 106. ISBN 90-04-11244-8.
- Zuijderduijn, Jaco (2009). Medieval Capital Markets. Markets for renten, state formation and private investment in Holland (1300-1550). Leiden/Boston: Brill. ISBN 978-90-04-17565-5.
- Catoni, Giuliano. "BONSIGNORI". Dizionario Biografico degli Italiani. Retrieved 20 December 2011.