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|Centuries:||14th century – 15th century – 16th century|
|Decades:||1420s 1430s 1440s – 1450s – 1460s 1470s 1480s|
|Years:||1447 1448 1449 – 1450 – 1451 1452 1453|
|1450 by topic|
|Arts and science|
|Architecture - Art|
|State leaders - Sovereign states|
|Birth and death categories|
|Births - Deaths|
|Establishments and disestablishments categories|
|Establishments - Disestablishments|
|Art and literature|
|1450 in poetry|
|Ab urbe condita||2203|
|English Regnal year||28 Hen. 6 – 29 Hen. 6|
— to —庚午年十一月廿八日
|- Vikram Samvat||1506–1507|
|- Shaka Samvat||1372–1373|
|- Kali Yuga||4551–4552|
|- Ǹrí Ìgbò||450–451|
|Japanese calendar||Hōtoku 2
|Juche calendar||N/A (before 1912)|
|Julian calendar||1450 MCDL|
|Minguo calendar||462 before ROC
|Thai solar calendar||1993|
|Wikimedia Commons has media related to: 1450|
- February 7 – John de la Pole, 2nd Duke of Suffolk, marries Lady Margaret Beaufort.
- March – French troops under Guy de Richemont besiege the English commander in France, Edmund Beaufort, 1st Duke of Somerset, in Caen.
- April 15 – Battle of Formigny: French troops under the Comte de Clermont defeat an English army under Sir Thomas Kyriel and Sir Matthew Gough which was attempting to relieve Caen.
- May 8 – Jack Cade's Rebellion: Kentishmen revolt against King Henry VI.
- May 9 – 'Abd al-Latif Mirza (a Timurid monarch) is assassinated.
- May 13 – Charles VIII of Sweden (who was also serving as Carl I of Norway) is declared deposed from the later throne in favor of Christian I of Denmark.
- June 18 – Battle of Seven Oaks: Jack Cade's rebels are driven from London by loyal troops, bringing about the collapse of the rebellion.
- July 6 – Caen surrenders to the French.
- July 12 – Jack Cade was slain in a revolt against British King Henry VI.
- August 12 – Cherbourg, the last English territory in Normandy, surrenders to the French.
- October 5 – Jews were expelled from Lower Bavaria by order of Ludwig IX.
- November 3 – The University of Barcelona is founded.
- November 23 – First Siege of Krujë: Albanian victory; Ottoman army of approximately 100,000 men retreats from Albania.
Date unknown 
- Wolves enter Paris and kill 40 citizens.
- The Age of Discovery begins.
- Machu Picchu (Quechua: Machu Pikchu, "Old mountain") a pre-Columbian Inca site located 2,400 meters (7,875 ft) above sea level believed to be under construction.
- May 18 – Piero Soderini, Florentine statesman (d. 1513)
- August 18 – Marko Marulic, Croatian poet (d. 1524)
- date unknown
- Kamāl ud-Dīn Behzād, leader of the Herat school
- Hieronymus Bosch, Dutch painter (d. 1516)
- Gaspar Corte-Real, Portuguese explorer (d. 1501)
- Josquin des Prez, Dutch composer (d. 1521)
- Heinrich Isaac, Franco-Flemish composer (d. 1517)
- Hugh Oldham, Bishop of Exeter (d. 1519)
- Pietro Antonio Solari, Italian architect (d. 1493)
- Petrus Thaborita, Dutch historian and monk (d. 1527)
- January 9 – Adam Moleyns, Bishop of Chichester
- February 9 – Agnès Sorel, mistress of Charles VII of France (b. 1421)
- May 2 – William de la Pole, 1st Duke of Suffolk, English military leader (born 1396)
- May 9 – 'Abd al-Latif, ruler of Transoxonia
- May 18 – Sejong the Great of Joseon, ruler of Korea (b. 1397)
- June 10 – William Tresham, English politician
- July 2 – Ranuccio Farnese il Vecchio, Italian condottiero (b. c.1390)
- July 4 – James Fiennes, 1st Baron Saye and Sele
- July 18 – Francis I, Duke of Brittany (b. 1414)
- July 28 – Cecily Neville, Duchess of Warwick (b. 1424)
- August 15 – Alberto da Sarteano, Italian Franciscan friar and papal legate (b. 1385)
- August 27 – Reginald West, 6th Baron De La Warr, English politician (b. 1395)
- August 31 – Isabella of Navarre, Countess of Armagnac (b. 1395)
- September 16 – Louis Aleman, French cardinal
- November 3 – Paola Colonna, Lady of Piombino (born c.1378)
- November 5 – John IV, Count of Armagnac (born 1396)
- "Historic Sanctuary of Machu Picchu — UNESCO World Heritage Centre". UNESCO. 2006. Retrieved 9 December 2006.