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|Centuries:||14th century – 15th century – 16th century|
|Decades:||1430s 1440s 1450s – 1460s – 1470s 1480s 1490s|
|Years:||1463 1464 1465 – 1466 – 1467 1468 1469|
|1466 by topic|
|Arts and science|
|Architecture - Art|
|State leaders - Sovereign states|
|Birth and death categories|
|Births - Deaths|
|Establishments and disestablishments categories|
|Establishments - Disestablishments|
|Art and literature|
|1466 in poetry|
|Ab urbe condita||2219|
|Bahá'í calendar||−378 – −377|
|English Regnal year||5 Edw. 4 – 6 Edw. 4|
|Chinese calendar||乙酉年 (Wood Rooster)
4162 or 4102
— to —
丙戌年 (Fire Dog)
4163 or 4103
|- Vikram Samvat||1522–1523|
|- Shaka Samvat||1388–1389|
|- Kali Yuga||4567–4568|
|Japanese calendar||Kanshō 7 / Bunshō 1
|Minguo calendar||446 before ROC
|Thai solar calendar||2009|
|Wikimedia Commons has media related to 1466.|
- June – Second Siege of Krujë: Mehmed II leads an army of 150,000 in an attempt to quash the Albanian resistance by taking Krujë. The Albanians repulse him and the Ottoman army retreats from Albania.
- August 26 – A conspiracy against Piero di Cosimo de' Medici, led by Luca Pitti and Borso d'Este, is discovered and put down in Florence.
- October 18 – Erik Axelsson Tott replaces Jöns Bengtsson Oxenstierna as Regent of Sweden.
- October 19 – The Thirteen Years' War ends with the Second Peace of Thorn.
- The Chimú Empire is conquered by troops of the Inca.
- The Mentelin Bible, the first printed German language Bible, is produced.
- Louis XI of France introduces silk weaving to Lyon.
- Collapse of the Kingdom of Georgia into anarchy and its subsequent fragmentation into rival states of Kartli, Kakheti, Imereti, Samtskhe-Saatabago and a number of principalities, which is finalised in 1490 when Constantine II of Georgia has to recognize his rival monarchies.
- The 2nd largest bell of St. Peter's Church in Fritzlar was founded by Meister Goswin aus Fritzlar.
- February 11 – Elizabeth of York, queen of Henry VII of England (d. 1503)
- June 18 – Ottaviano Petrucci, Italian music printer (d. 1539)
- August 10 – Francesco II Gonzaga, Marquess of Mantua (d. 1519)
- September 9 – Ashikaga Yoshitane, Japanese shogun (d. 1523)
- October 27 – Erasmus, Dutch philosopher (d. 1536)
- November 30 – Andrea Doria, Italian naval leader (d. 1560)
- March 8 – Francesco I Sforza, Duke of Milan (b. 1401)
- October 30 – Johann Fust, German printer (b. c. 1400)
- December 13 – Donatello, Italian artist (b. 1386)
- date unknown