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|Centuries:||14th century – 15th century – 16th century|
|Decades:||1460s 1470s 1480s – 1490s – 1500s 1510s 1520s|
|Years:||1495 1496 1497 – 1498 – 1499 1500 1501|
|1498 by topic|
|Arts and science|
|Architecture - Art|
|State leaders - Sovereign states|
|Birth and death categories|
|Births - Deaths|
|Establishments and disestablishments categories|
|Establishments - Disestablishments|
|Art and literature|
|1498 in poetry|
|Ab urbe condita||2251|
|English Regnal year||13 Hen. 7 – 14 Hen. 7|
— to —戊午年閏十一月十九日
|- Vikram Samvat||1554–1555|
|- Shaka Samvat||1420–1421|
|- Kali Yuga||4599–4600|
|- Ǹrí Ìgbò||498–499|
|Japanese calendar||Meiō 7
|Juche calendar||N/A (before 1912)|
|Julian calendar||1498 MCDXCVIII|
|Minguo calendar||414 before ROC
|Thai solar calendar||2041|
|Wikimedia Commons has media related to: 1498|
- January 25 – Portuguese explorer Vasco da Gama visits Quelimane and Mozambique in southeastern Africa.
- February – Da Gama reaches Malindi in modern-day Kenya.
- May 20 – Portuguese navigator Vasco da Gama arrives at Calicut (now Kozhikode), India, becoming the first European to get there by sailing around Africa, thus discovering the maritime route to India. He finds a local Arab merchant who is able to interpret for him.
- May 23 – Girolamo Savonarola, ruler of Florence, is executed for criticizing the Pope.
- June – Niccolò Machiavelli is elected by the Great Council as the second chancellor of the Republic of Florence.
- Summer – The final Welsh revolt of the medieval era breaks out in Meirionydd, North Wales; Harlech Castle is captured by the rebels before the revolt in suppressed.
- July 31 – On his third voyage to the Western Hemisphere, Christopher Columbus becomes the first European to discover the island of Trinidad.
- August 1 – Columbus discovers the mouth of the Orinoco.
- August 4–12 – Columbus explores the Gulf of Paria.
- Voyage of João Fernandes Lavrador and Pedro Barcelos to Greenland during which they discover the land which they name Labrador.
- Probable date at which Leonardo da Vinci completes painting The Last Supper on the refectory wall of Santa Maria delle Grazie (Milan).
- April 9 – Jean, Cardinal of Lorraine, French churchman (d. 1550)
- June 1 – Maarten van Heemskerck, Dutch painter (d. 1574)
- November 15 – Eleanor of Austria, Queen of Portugal and France (d. 1558)
- November 30 – Andrés de Urdaneta, Spanish Friar (d. 1568)
- December 19 – Andreas Osiander, German Protestant theologian (d. 1552)
- date unknown
- Giulio Clovio, (Juraj Julije Klovic) Dalmatian miniaturist and illustrator (d. 1578)
- Anna of Masovia, Polish princess (d. 1557)
- Meera, Rajput princess (d. 1547)
- Sagara Taketō, Japanese retainer (d. 1551)
- Pier Paolo Vergerio, Italian religious reformer (d. 1565)
- Felix Manz, leader of the Swiss Anabaptists (d. 1527)
- February 4 – Antonio del Pollaiolo, Italian painter (b. c. 1432)
- March 24 – Edward Stafford, 2nd Earl of Wiltshire (b. 1470)
- April 7 – King Charles VIII of France (b. 1470)
- May 23 – Girolamo Savonarola, Italian religious reformer and ruler of Florence (b. 1452)
- August 24 – Isabella, eldest daughter of Isabella I of Castile and Ferdinand II of Aragon (b. 1470)
- September 16 – Tomás de Torquemada, first grand inquisitor (b. 1420)
- December 7 – Alexander Hegius von Heek, German humanist (b. c. 1443)
- date unknown
- probable – Johannes Martini, Flemish composer (b. c. 1440)