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This article is about the year 1545.
|Centuries:||15th century – 16th century – 17th century|
|Decades:||1510s 1520s 1530s – 1540s – 1550s 1560s 1570s|
|Years:||1542 1543 1544 – 1545 – 1546 1547 1548|
|1545 by topic|
|Arts and science|
|Lists of leaders|
|Birth and death categories|
|Establishments and disestablishments categories|
|Ab urbe condita||2298|
|Bahá'í calendar||−299 – −298|
|English Regnal year||36 Hen. 8 – 37 Hen. 8|
|Chinese calendar||甲辰年 (Wood Dragon)
4241 or 4181
— to —
乙巳年 (Wood Snake)
4242 or 4182
|- Vikram Samvat||1601–1602|
|- Shaka Samvat||1467–1468|
|- Kali Yuga||4646–4647|
|Japanese calendar||Tenbun 14
|Minguo calendar||367 before ROC
|Thai solar calendar||2088|
|Wikimedia Commons has media related to 1545.|
- February 27 – Battle of Ancrum Moor: The Scots are victorious over numerically superior English forces.
- June 13 – Spanish explorer Yñigo Ortiz de Retez sets out to navigate the northern coast of New Guinea.
- July 18–19 – Battle of the Solent between English and French fleets. The engagement is inconclusive but on July 19 Henry VIII of England's flagship, the Mary Rose, sinks.
- c. July 21 – Battle of Bonchurch: The English reverse an attempted French invasion of the Isle of Wight off the coast of England as part of the Italian Wars.
- c. September – Mobye Narapati succeeds as ruler of the Ava Kingdom and offers peace to the Taungoo Dynasty, ending the Toungoo–Ava War (1538–45) and leaving the Taungoo as the dominant rulers in modern-day Burma.
- October – Siege of Kawagoe Castle begins as part of an unsuccessful attempt by the Uesugi clan to regain Kawagoe Castle from the Late Hōjō clan in Japan.
- December 13 – The Council of Trent officially opens (closes 1563).
- Battle of Sokhoista: The army of the Ottoman Empire defeats an alliance of Georgian dynasts.
- In Ming Dynasty China a large failure of the harvest in Henan province occurs due to excessive rainfall, which drives up the price of wheat and forces many to flee their rural counties; those who stay behind are forced to survive by eating leaves, bark, and human flesh.
- Silver is discovered at Potosí, Bolivia.
- March 2 – Thomas Bodley, English diplomat and library founder (d. 1613)
- April 2 – Elizabeth of Valois, queen of Philip II of Spain (d. 1568)
- April 28 – Yi Sun-sin, Korean naval leader (d. 1598)
- July 8 – Don Carlos of Spain, son of Philip II of Spain (d. 1568)
- August 1 – Andrew Melville, Scottish theologian and religious reformer (d. 1622)
- August 27 – Alexander Farnese, Duke of Parma (d. 1592)
- December 7 – Henry Stuart, Lord Darnley, consort of Mary, Queen of Scots (d. 1567)
- date unknown
- George Bannatyne, collector of Scottish poems (d. 1608)
- John Field, British Puritan clergyman and controversialist (d. 1588)
- John Gerard, English botanist (d. 1612)
- William Morgan, Welsh Bible translator (d. 1604)
- Azai Nagamasa, Japanese nobleman (d. 1572)
- Mashita Nagamori, Japanese warlord (d. 1615)
- January 16 – George Spalatin, German reformer (b. 1484)
- February 12 or April 2 – Stanisław Odrowąż, Polish noble (b. 1509)
- April 3 – Antonio de Guevara, Spanish chronicler and moralist (b. 1481)
- April 10 – Costanzo Festa, Italian composer (b. 1495)
- April 22 – Louis X, Duke of Bavaria (b. 1496)
- May – Agnes Howard, Duchess of Norfolk, English noblewoman (b. c. 1477)
- May 22 – Sher Shah Suri, Indian ruler (b. 1486)
- June 12 – Francis I, Duke of Lorraine (b. 1517)
- July 7 – Pernette Du Guillet, poet (b. c. 1520)
- August 24 – Charles Brandon, 1st Duke of Suffolk, English politician and husband of Mary Tudor (b. c. 1484)
- August 27 – Piotr Gamrat, Polish Catholic archbishop (b. 1487)
- September – Hans Baldung, German artist (b. 1480)
- September 24 – Albert of Mainz, elector and archbishop of Mainz (b. 1490)
- October 18 – John Taverner, English composer (b. c. 1490)
- date unknown