5 February - An observer in Wilmington, North Carolina, reports to the Edinburgh newspaper Caledonian Mercury that three ships were seized by British Men of War on the charge of carrying official documents without stamps. The strict enforcement causes seven other ships to leave Wilmington for other ports.
20 February - The Pennsylvania Gazette reports that a British sloop outside of Wilmington, North Carolina seized one sloop sailing from Philadelphia and one sloop sailing from Saint Christopher on the charge of carrying official documents without stamps. In response, local residents threaten to burn a Royal Man of War attempting to deliver stamps to Wilmington, forcing the ship to return to the mouth of the Cape Fear River.
27 November - An observer in New York City reports to the Pennsylvania Gazette that a British Sloop of War is searching all vessels passing near Cape Lookout, North Carolina, and that some vessels have been seized.
Henry Cavendish publishes his paper "On Factitious Airs". This is generally credited to show the discovery of hydrogen, since it describes the density of 'inflammable air', which formed water on combustion.