Beginning its 11th year, Nebraska was starting out with a new head coach for the 9th time after replacing A. Edwin Branch at the end of a 1-7-1 season. Also, the team had officially adopted its new nickname "Cornhuskers" beginning this year, after the term was coined by Charles "Cy" Sherman in one of his pieces written for the Nebraska State Journal during the 1899 season.
The Cornhuskers got their first scrimmage preseason tuneup under new coach Booth with another exhibition game against Lincoln High School, a 22-0 shutout to extend their record over the high schoolers to 3-0. 
For the first time, the Cornhuskers went head to head against a team made up of former Cornhuskers, in this second exhibition game of the season. Apparently the graduates still had what it takes, as the game ended in a 0-0 draw. 
Coach Booth's first official game of his career at Nebraska was a refreshing change from the disastrous previous season, as the Cornhuskers had little difficulty putting up 30-0 shutout of the Cyclones in Lincoln. Counting the exhibition games, this was the third game in a row where the Nebraska defense held the other team to zero points, and Nebraska pulled into the series lead, 3-2. 
Heavy winds interfered with both teams as they attempted to get on the scoreboard, and the day ended with a single touchdown and late safety by Nebraska being the only scores. The shutout streak continued, and Drake fell behind Nebraska in the series, 1-2. 
The Kansas City Medics put up a fight as Nebraska faced them in Kansas City for the second year in a row, and despite the best efforts of both teams, the defensive units carried the day and sent both teams off the field scoreless in a 0-0 tie. This was the last times these teams met, with the KC Medics owning the hard-fought series with Nebraska 2-1-2. 
Just two days after the battle in Kansas City, the Cornhuskers met Tarkio on the field for the third and final time, but on Tarkio's home field for the first time. Nebraska's first and only score was disputed by Tarkio players and fans, but the score was upheld by the officials. Nebraska failed to capitalize on a later opportunity to put up undisputed points, and the official score remained 5-0 for the rest of the game. The final outcome was disputed strongly enough in Tarkio that the home town paper reported the next day that the score had been a 0-0 tie. 
Nebraska's unbeaten and unscored upon roll continued with a strong effort against Missouri in Columbia. One Cornhusker score in each half summed the points of the game, which featured much punting and changes of possession. Nebraska improved to 6-3 over Missouri.
The day belonged entirely to the Cornhuskers as they rolled to an easy shutout victory over Grinnell in Lincoln. The visitors' best shot at avoiding the shutout fell short with a missed 25-yard field goal attempt. This evened the Grinnell-Nebraska series at 2-2. 
Nebraska closed out its 9th straight shutout game, counting the exhibition games, against Kansas in Lawrence. No opponents had scored on the Cornhuskers even once during the entire season to date, and Nebraska's series record deficit with Kansas to 4-5. 
Nebraska's unbeaten run came to an end as the Cornhuskers hosted Minnesota for the first game of what would become a long and storied rivalry in later years. The Gophers were on average larger and taller than the Cornhuskers, posing a formidable challenge. Despite the loss, Nebraska still managed, through halftime adjustments, to outscore Minnesota in the second quarter, and those 12 points were more than any other opponent had put up against Minnesota in any other game of their season.