South Dakota seemed at first to have the key to holding off Nebraska, but once the Cornhuskers managed to find the end zone, the Coyote defense lost their containment of the Cornhuskers. Nebraska's lead in the series was now 4-1. 
It had been two years since Grinnell appeared in Lincoln, but it was more of the same for them upon their return. Nebraska failed to capitalize on several Grinnell miscues in the first half, but eventually the Cornhuskers pulled away for the clear win to extend their series lead to 5-2. 
The now-annual grudge match, where Nebraska continuously seemed to find futility in their repeated attempts to knock off Minnesota, was a repeat of the last several contests. Things were looking up for the Cornhuskers when they capitalized on a Golden Gopher error to score first, but a couple of field goals by Minnesota reversed the lead and yet again sent Nebraska home with a loss, seriously lagging in the series 1-6. 
Colorado arrived in Lincoln with designs to avenge some earlier losses to the Cornhuskers, but were sent home disappointed after being handed a 22-8 decision resulting in part from several Colorado mistakes during the game. Nebraska's lead in the series was extended to 5-1.
Nebraska survived a scare after the Cyclones were at one point leading the Cornhuskers 9-4 in the second half. Both teams made mistakes, but it was Nebraska with more points when time expired. Iowa State fell further behind in the series, 3-6. This game is under dispute, as Iowa State claims they won by a final score of 13-10. This is because on a late-game field goal attempt, the ball hit the ground well short of the uprights, but bounced through. 
The game with Kansas was the only conference match for Nebraska this year, since the Cornhuskers had only recently rejoined a conference and were unable to schedule the other conference teams on the relatively short notice. This one win, however, was enough for Nebraska to claim a share of the conference title, and improved their record over the Jayhawks to 8-6. 
Nebraska suddenly found their machine to be well-oiled and effective, traveling to Denver to meet the Pioneers for the second time, and recording a convincing 63-0 shutout victory to celebrate the 100th Nebraska program victory, also moving up to 2-0 against Denver. 
The Cornhuskers demolished Doane in every way, shutting them out 85-0. This was the highest score and margin of victory ever in the history of Antelope Field, and the second-highest score and margin of victory in program history at that time, second only to the 1905 smashing of Creighton in Omaha, 102-0. Nebraska was now 11-2 over Doane in the longest still-active series in Nebraska's history at that time. 
Nebraska closed out 1907 facing St Louis for the first and only time, no small task considering the Billikens had gone undefeated in the previous season. The Cornhuskers made it within the 2-yard line, and on another attempt within inches of the end zone, but were unable to convert and avoid the season-ending shutout loss. 
Coach Cole wrapped up his first season with the Cornhuskers with relative success, his one-season record of 8-2-0 (.800) raising the program's total slightly to 101-39-5 (.714). Nebraska's win in their one conference game, against Kansas, was enough to put Nebraska into a tie for first place in the league.