The Yankees were back after a one-year hiatus, having won 13 of their last 14 Series games and 28 of their last 31.
This was the first Subway Series between the Brooklyn Dodgers and New York Yankees, who had already faced the crosstown New York Giants five times, and the Series was now 1–0 in favor of the Bronx Bombers. These two teams would meet a total of seven times from 1941–1956 — the Dodgers' only victory coming in 1955 — with an additional four matchups after the Dodgers left for Los Angeles, most recently in 1981.
With the veteran Fitzsimmons dueling young southpaw Russo, there was no score into the top of the seventh. With two outs, Russo lined a drive off Fitz's knee that broke the kneecap. The ball caromed into Pee Wee Reese's glove for the third out, but Fitzsimmons was through. Hugh Casey, who came out to pitch in the eighth for Brooklyn, promptly gave up four hits and two runs, and Russo hung on to win, 2–1.
The Dodgers led by one run after eight innings—and still led with two out, two strikes, and no runner on base in the ninth—but would lose the game. Tommy Henrich swung and missed, which would have ended the game, but Dodger catcher Mickey Owen failed to catch the ball and Henrich reached first base. Owen recollected the incident:
It was a great breaking curve that I should have had, but I guess the ball hit the side of my glove. It got away from me, and by the time I got hold of it, near the corner of the Brooklyn dugout, I couldn't have thrown anybody out at first.
Joe DiMaggio followed with a single and Charlie Keller hit a double to drive in Henrich and DiMaggio and take the lead. Bill Dickey would follow up with a walk and, along with Keller, score on a Joe Gordon double to make the final score 7–4.
Meyer Berger of The New York Times, then its local color reporter, covered the events in "Casey in the Box", a poem derived from the 1888 classic "Casey at the Bat".
The only excitement of the game occurred in the fifth inning, when Wyatt and Joe DiMaggio almost came to blows on the mound as Joe returned to the dugout after flying out. Wyatt had low-bridged DiMaggio was cutting across the infield some sharp words were exchanged. The umpires separated the men, and the game rolled forward to its—for Brooklyn—dreary conclusion.