The 1943 All-Ireland Senior Hurling Championship was the 57th staging of the All-Ireland hurling championship since its establishment by the Gaelic Athletic Association in 1887. The championship began on 2 May 1943 and ended on 5 September 1943.
The All-Ireland Senior Hurling Championship was run on a provincial basis as usual. All games were played on a knockout basis whereby once a team lost they were eliminated from the championship. The format for the All-Ireland series of games ran as follows:
Galway, a team who faced no competition in the Connacht Championship, entered the championship at the All-Ireland quarter-final stage where they played the Ulster champions. The winners of this game advanced to the lone All-Ireland semi-final.