The 1988 Guarujá Open was a tennis tournament held in Guarujá in Brazil and played on clay courts. It was part of the 1988 Nabisco Grand Prix. The tournament took place from January 25 through February 1, 1988.
Luiz Mattar defeated Eliot Teltscher 6–3, 6–3
- It was Mattar's only title of the year and the 4th of his career.
Ricardo Acuña / Luke Jensen defeated Javier Frana / Diego Pérez 6–1, 6–4
- It was Acuña's only title of the year and the 3rd of his career. It was Jensen's only title of the year and the 1st of his career.