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1O or 1-O may refer to:
- 1o Sector, see Primary sector of the economy
- Glucogallin, or 1-O-galloyl-beta-D-glucose
- Isomalt, or 1-O-alpha-D-glucopyranosyl-D-mannitol
- Corilagin, or Beta-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose
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