2'-Acetoxycocaine

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2'-Acetoxycocaine
2'-Acetoxycocaine.svg
Identifiers
CAS number 192648-66-1 YesY
PubChem 10713606
ChemSpider 8888946 YesY
Jmol-3D images Image 1
Properties
Molecular formula C19H23NO6
Molar mass 361.39 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

2'-Acetoxycocaine is a cocaine analog, with a quicker effect onset than cocaine. The acetoxy branch renders the molecule a QSAR of a 4-fold increase over cocaine in its binding potency for the dopamine transporter & a 35-fold enhanced affinity for the norepinephrine transporter. It also has a reduced selectivity for the serotonin transporter.[1]

See also[edit]

References[edit]

  1. ^ Seale, TW; Avor, K; Singh, S; Hall, N; Chan, HM; Basmadjian, GP (1997). "2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding". Neuroreport 8 (16): 3571–5. doi:10.1097/00001756-199711100-00030. PMID 9427328.