2,4-Dichlorobenzyl alcohol

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2,4-Dichlorobenzyl alcohol
Dichlorobenzyl alcohol.png
Names
IUPAC name
(2,4-Dichlorophenyl)methanol
Other names
Dybenal
Rapidosept
Myacide SP
Identifiers
ATC code R02AA03
1777-82-8 N
ChEBI CHEBI:48220 YesY
ChemSpider 14918 YesY
Jmol-3D images Image
Image
PubChem 15684
Properties
C7H6Cl2O
Molar mass 177.03 g/mol
Melting point 57 °C (135 °F; 330 K)
Boiling point 150 °C (302 °F; 423 K) 25 mmHg
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils, Lorsept or Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (600μg) has been found to deactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus.[1] A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing.[2]

References[edit]

  1. ^ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral chemistry and chemotherapy 16 (2): 129–34. PMID 15889535. 
  2. ^ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study.". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.