2,4-Dichlorobenzyl alcohol
| 2,4-Dichlorobenzyl alcohol | |
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(2,4-Dichlorophenyl)methanol |
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Other names
Dybenal |
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| Identifiers | |
| CAS number | 1777-82-8  |
| PubChem | 15684 |
| ChemSpider | 14918 |
| ChEBI | CHEBI:48220 |
| Jmol-3D images | Image 1 Image 2 |
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| Properties | |
| Molecular formula | C7H6Cl2O |
| Molar mass | 177.03 g/mol |
| Melting point |
57-60 °C |
| Boiling point |
150 °C (25 mmHg) |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils or Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (600μg) has been found to deactivate Respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus.[1] A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5–10 minutes after brushing.[2]
[edit] References
- ^ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral chemistry and chemotherapy 16 (2): 129–34. PMID 15889535.
- ^ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study.". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.
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