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Systematic (IUPAC) name
Clinical data
1080-95-1 YesY
Chemical data
Formula C13H18N2
202.30 g/mol
 YesY (what is this?)  (verify)

2,N,N-Trimethyltryptamine, 2,N,N-TMT, or 2-Me-DMT is a tryptamine derivative that is a psychedelic drug. It was invented by Alexander Shulgin and reported in his book TiHKAL (#34).[1] It is claimed to show psychoactive effects at a dosage of 50–100 mg orally, but these are relatively mild compared to other similar drugs, suggesting that while the 2-methyl group has blocked the binding of metabolic enzymes, it is also interfering with binding to the 5HT2A receptor target that mediates the hallucinogenic effects of these drugs.

See also[edit]


  1. ^ Erowid Online Books : "TIHKAL" - #34 2-ME-DMT

External links[edit]