2-Aminopyridine

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2-Aminopyridine
2-aminopyridine.svg
Identifiers
CAS number 504-29-0 YesY
PubChem 10439
ChemSpider 10008 YesY
ChEMBL CHEMBL21619 YesY
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C5H6N2
Molar mass 94.11 g mol−1
Appearance colourless solid
Melting point 59-60 °C
Boiling point 210 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

2-Aminopyridine is an organic compound with the formula H2NC5H4N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.[1]

Structure[edit]

Although 2-hydroxypyridine exists in significant amounts as the pyridone tautomer, the related imine tautomer (HNC5H4NH) is less important for 2-aminopyridine.

References[edit]

  1. ^ Shinkichi Shimizu, Nanao Watanabe, Toshiaki Kataoka, Takayuki Shoji, Nobuyuki Abe, Sinji Morishita, Hisao Ichimura "Pyridine and Pyridine Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry 2000, Wiley-VCH, Weinheim. doi:10.1002/14356007.a22_399

External links[edit]