2-Methyl-MDA

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2-Methyl-MDA
2-Methyl-MDA skeletal.svg
Systematic (IUPAC) name
1-(4-methyl-1,3-benzodioxol-5-yl)propan-2-amine
Clinical data
Legal status
Routes Oral
Identifiers
CAS number 691876-73-0 N
204916-87-0 (HCl)
ATC code None
PubChem CID 10104064
ChemSpider 8279591 YesY
ChEMBL CHEMBL6391 YesY
Chemical data
Formula C11H15NO2 
Mol. mass 193.242 g/mol
 N (what is this?)  (verify)

2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen[citation needed] and psychedelic[citation needed] drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux.[1] 2-Methyl-MDA is more potent than MDA, although it is not as potent as 5-methyl-MDA.[1] However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.[1]

See also[edit]

References[edit]

  1. ^ a b c Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE (March 1998). "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry 41 (6): 1001–5. doi:10.1021/jm9705925. PMID 9526575.