2-Methyl-MDA

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2-Methyl-MDA
2-Methyl-MDA skeletal.svg
Systematic (IUPAC) name
1-(4-methyl-1,3-benzodioxol-5-yl)propan-2-amine
Clinical data
Legal status Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries)
Routes Oral
Identifiers
CAS number 691876-73-0 N
204916-87-0 (HCl)
ATC code None
PubChem CID 10104064
ChemSpider 8279591 YesY
ChEMBL CHEMBL6391 YesY
Chemical data
Formula C11H15NO2 
Mol. mass 193.242 g/mol
 N (what is this?)  (verify)

2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen[citation needed] and psychedelic[citation needed] drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux.[1] 2-Methyl-MDA is more potent than MDA, although it is not as potent as 5-methyl-MDA.[1] However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA.[1]

See also[edit]

References[edit]

  1. ^ a b c Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE (March 1998). "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry 41 (6): 1001–5. doi:10.1021/jm9705925. PMID 9526575.