10 January - The Prime Minister's wife, Cherie Blair, is fined for not having a valid train ticket with her during her journey from Blackfriars to Luton station. She claimed only to have Portuguese currency with her at the time and couldn't find a machine where she could use her credit card.
12 January - It is announced that former Chilean dictator, Augusto Pinochet, is to be sent home after the Home Secretary, Jack Straw, accepted "unequivocal and unanimous" medical evidence that Pinochet is unfit to stand trial in Spain on charges of torture. 
31 January – Dr. Harold Shipman in sentenced to life imprisonment after being found guilty of murdering 15 patients in Greater Manchester between 1995 and 1998. He is also sentenced to four years in prison, to run concurrently, for forging the will of one of his victims.
April – The Ministry of Defence publishes a booklet Soldiering – The Military Covenant which introduces the term into public discourse referring to the mutual obligations between the nation and its armed forces.
14 April – Kenneth Noye, the so-called "M25 killer", sentenced to life imprisonment.
19 April – Tony Martin is sentenced to life imprisonment for the murder of a 16-year-old burglar he shot dead at his Norfolk farmhouse eight months ago. He is also convicted of the attempted murder of Brendon Fearon, the burglar who was wounded when Martin opened fire and killed Fred Barras.
17 June – Alan Shearer, who is set to retire from international football after the European Championships, scores the only goal as England beat holders Germany 1–0 in the second group game.
18 June – Following a series of hooliganism incidents by England fans, UEFA threatens to expel England from Euro 2000 if there is any further trouble.
20 June – England's hopes of winning Euro 2000 are ended when they lose 3–2 to Romania in the final group game, again after taking the lead earlier in the game.
21 June – Repeal in Scotland of controversial Section 28 of the Local Government Act 1988 which prevented local authorities from "promoting homosexuality". Section 28 is not repealed in the rest of the UK until 2003.
30 June – David Copeland is found guilty of causing the three nail bomb attacks in London last year. He is sentenced to life imprisonment and the trial judge recommends that he should serve at least 30 years before being considered for parole, meaning that he is likely to remain in prison until at least 2029 and the age of 54.
September – Ford unveils its all-new second generation Mondeo large family car, which is due on sale towards the end of this year.
8 September – UK fuel protests: Protesters block the entrances to oil refineries in protest against high fuel prices. Panic buying by motorists leads to nationwide petrol shortages, with between 75–90% of all UK petrol stations closing due to low supplies in the following week.
14 September – After beginning the year 20 points behind the Labour government in the opinion polls, the Conservative opposition's hopes of winning the next election (due to be held within 18 months) are boosted when they come two points ahead of Labour on 38% in a MORI opinion poll. 
15 September – 1 October – Great Britain competes at the Olympics in Sydney and wins 11 gold, 10 silver and 7 bronze medals.
18 September – Survivors of the Southall and Ladbroke Grove rail disasters criticise Railtrack for putting costs ahead of safety and causing a series of blunders which led to the tragedies.
7 October – Wembley Stadium closes after 77 years. It is set to re-open in 2003 following a complete reconstruction that will see its capacity raised to 90,000 all-seated. In the final game at the old stadium, the England football team loses 1–0 to Germany in their opening qualifying game for the 2002 World Cup and manager Kevin Keegan resigns after 18 months in charge.
16 October – The BBC's main evening news show moves to 10:00 pm; the following year ITV1 will move its news back to the same time slot and broadcasts in direct competition.
23 October – After the fuel protests were solved, Labour support has been restored, according to the latest MORI opinion poll which shows them 13 points ahead of the Conservatives with 45% of the vote.
23 November – Double by-election held in Glasgow Anniesland to elect successors to Donald Dewar's seats in both the UK Parliament and the Scottish Parliament. Labour holds both seats with swings to the SNP of 6% and 7%.