On October 27, Larry Foote earned a share of the single-game conference record of 7 tackles for a loss, becoming the third conference athlete to do so. He also holds a share of the national record, becoming the third player to do so since the NCAA recognized it as a stat.
Marquise Walker was the Big Ten receiving statistical champion with 7.5 receptions per conference game and 7.2 reception per game. On September 8 against Washington and November 24 against Ohio State he posted 15 receptions breaking the record of 12 set in 1958 by Brad Myers and tied in 1996 by Tai Streets. The record still stands. During the season he set the school record for single-season receptions (86), surpassing Jack Clancy's 1966 record of 76; career receptions (176), surpassing Anthony Carter's 161 set in 1982; consecutive games with a reception (32), surpassing Mercury Hayes's 30 set in 1995; and single-season reception yards, surpassing David Terrell's record set the prior season. Braylon Edwards surpassed all of these records in 2004.
The team earned the Big Ten rushing defense statistical championships for all games by holding opponents to 89.1 yards per game. The team also earned the Big Ten rushing defense statistical championships for conference games by holding opponents to 95.4 yards per game. The team earned the Big Ten passing defense statistical championships for conference games by holding conference opponents to 190.8 yards per game, although Ohio State won the title for all games. They also ranked first in passing efficiency defense for both conference games (103.5) and with Ohio State leading for all games. The team led the conference in total defense for conference games (286.1) and all games (316.4). The team led the Big Ten Conference in scoring defense for conference games (16.9 points per game) and all games (19.8). They were the conference leaders in quarterback sacks for conference games (4.4 sacks per game) and all games (4.2 sacks per game).
John Navarre set the school single-season pass attempts record of 385, surpassing 350 by Tom Brady in 1998. He would rebreak his own record in each of the next two seasons.
Managers: Nate Bentz, Joe Harper, Craig Hisey, Brad Hoffman, Chris Lemaster, Adam Jahnke, Matt Kernen, Maggie Malone, Katie McNall, Craig Podolski, Rick Polanco, Brian Resutek, Victor Soto, Davon Wilson