2001 National League Division Series
|Dates:||October 9–October 12|
|Television:||Fox Family (Games 1–2)
Fox (Game 3)
|TV announcers:||Kenny Albert, Rod Allen (Games 1–2)
Mel Proctor, Rod Allen (Game 3)
|Dates:||October 9–October 14|
|Television:||Fox Family (Games 1–4)
Fox (Game 5)
|TV announcers:||Thom Brennaman, Steve Lyons (Games 1–2)
Joe Buck, Tim McCarver (Game 3–5)
|Umpires:||Bruce Froemming, Chuck Meriwether, Mike Winters, Brian Gorman, Jim Joyce, Mike Everitt (Astros–Braves, Games 1–2; Diamondbacks–Cardinals, Games 3–5)
Randy Marsh, John Hirschbeck, Larry Young, Tim Tschida, Dale Scott, Alfonso Márquez (Diamondbacks–Cardinals, Games 1–2; Astros–Braves, Game 3)
The 2001 National League Division Series (NLDS), the opening round of the 2001 National League playoffs, began on Tuesday, October 9, and ended on Sunday, October 14, with the champions of the three NL divisions—along with a "wild card" team—participating in two best-of-five series. The teams were:
- (1) Houston Astros (Central Division champion, 93–69) vs. (3) Atlanta Braves (Eastern Division champion, 88–74): Braves win series, 3–0.
- (2) Arizona Diamondbacks (Western Division champion, 92–70) vs. (4) St. Louis Cardinals (Wild Card, 93–69): Diamondbacks win series, 3–2.
The higher seed (in parentheses) had the home field advantage (Games 1, 2 and 5 at home), which was determined by playing record. Houston and St. Louis tied for the Central Division title, but Houston was awarded the division winner's playoff-seeding over St. Louis due to their 9–7 advantage in head-to-head play. Officially the two clubs were co-champions. Although the team with the best record was normally intended to play the wild card team, the Astros played the Braves, rather than the wild card Cardinals, because the Astros and Cardinals are in the same division.
The Diamondbacks and Braves went on to meet in the NL Championship Series (NLCS). The Diamondbacks became the National League champion, and defeated the American League champion New York Yankees in the 2001 World Series.
Houston Astros vs. Atlanta Braves 
Atlanta won the series, 3–0.
|1||October 9||Atlanta Braves – 7, Houston Astros – 4||Enron Field||2:51||35,553|
|2||October 10||Atlanta Braves – 1, Houston Astros – 0||Enron Field||2:41||35,704|
|3||October 12||Houston Astros – 2, Atlanta Braves – 6||Turner Field||2:33||39,923|
Arizona Diamondbacks vs. St. Louis Cardinals 
Arizona won the series, 3–2.
|1||October 9||St. Louis Cardinals – 0, Arizona Diamondbacks – 1||Bank One Ballpark||2:36||42,251|
|2||October 10||St. Louis Cardinals – 4, Arizona Diamondbacks – 1||Bank One Ballpark||3:15||41,793|
|3||October 12||Arizona Diamondbacks – 5, St. Louis Cardinals – 3||Busch Stadium (II)||3:36||52,273|
|4||October 13||Arizona Diamondbacks – 1, St. Louis Cardinals – 4||Busch Stadium (II)||2:47||52,194|
|5||October 14||St. Louis Cardinals – 1, Arizona Diamondbacks – 2||Bank One Ballpark||3:05||42,810|
Houston vs. Atlanta 
The Atlanta Braves won their tenth straight division title, despite having the worst record (88–74) among playoff teams. With that record, 2001 was also the Braves' worst season since 1990, when they had the worst record in baseball. The Houston Astros were in the playoffs for the seventh time, hoping to avenge two postseason losses in the 1990s to the Braves. At 93–69, and having home field advantage throughout the playoffs, the Astros were heavily favored to win this series.
Game 1, October 9 
|WP: Rudy Seánez (1–0) LP: Mike Jackson (0–1) Sv: John Smoltz (1)
ATL: Brian Jordan (1), Chipper Jones (1), Andruw Jones (1)
HOU: Brad Ausmus (1), Vinny Castilla (1)
In Game 1, Greg Maddux faced Wade Miller. Brian Jordan drove in the first two runs of the game, hitting a sac fly in the first and a solo homer in the fourth. But the Astros would strike back against Maddux. Brad Ausmus's two-run homer tied the game in the fifth for the Astros. Then Moisés Alou's groundout in the sixth gave the Astros the lead. But the Braves refused to concede. They struck for four runs in the eighth, an inning capped by Chipper Jones's dramatic three-run homer. Both teams would homer in the ninth but John Smoltz got the save as the Braves won 7–4.
Game 2, October 10 
|WP: Tom Glavine (1–0) LP: Dave Mlicki (0–1) Sv: John Smoltz (2)|
In Game 2, Tom Glavine and Dave Mlicki started a classic pitching duel. In the top of the second, B.J. Surhoff doubled to lead off the inning. Then Andruw Jones singled to the shortstop and an error by Julio Lugo put Surhoff on third. Rey Sánchez would then ground into a double play by Surhoff would score to make it 1–0 Braves. In all but two innings the Astros had a hit and they would strand five in the game. Glavine pitched eight innings and Smoltz recorded his second consecutive postseason save.
Game 3, October 12 
|WP: John Burkett (1–0) LP: Shane Reynolds (0–1)
HOU: Daryle Ward (1)
ATL: Paul Bako (1), Julio Franco (1), Chipper Jones (2)
In Game 3, Shane Reynolds faced John Burkett. In the bottom of the second, Paul Bako's two-run homer put the Braves up 2–0. In the third, Julio Franco homered to make it 3–0. Then a squeeze play by Bako in the fourth made it 4–0. Reynolds only lasted four innings and Burkett cruised until giving up a two-run homer to Daryle Ward in the sixth. Chipper Jones's two-run homer provided insurance in the bottom of the eighth and Smoltz once again dominated the ninth. Ausmus flied to center to end the series. Once again, the Astros had been denied by the Braves for their first ever postseason series win. This, to date, is the last postseason series win by the Braves.
Composite box 
|Total attendance: 111,180 Average attendance: 37,060|
Arizona vs. St. Louis 
The St. Louis Cardinals were making their second straight postseason appearance and they hoped to avenge their NLCS loss against the New York Mets in 2000. The Arizona Diamondbacks were making their second playoff appearance and they too were stunned by the Mets in 1999, having won 100 games that year.
Game 1, October 9 
|WP: Curt Schilling (1–0) LP: Matt Morris (0–1)|
Game 1 was a game of excellent starting pitching. Matt Morris faced Curt Schilling, who made the most of his first playoff start in eight years. Both pitchers were on even terms until the bottom of the fifth when Arizona struck first when Steve Finley singled home Damian Miller. The game remained 1–0 as Schilling managed to pitch a complete-game three-hit shutout.
Game 2, October 10 
|WP: Woody Williams (1–0) LP: Randy Johnson (0–1) Sv: Steve Kline (1)
STL: Albert Pujols (1)
In Game 2, Woody Williams faced Randy Johnson. Johnson seemingly had the Cardinals in the first when he got Plácido Polanco to ground into a double play. But Edgar Rentería walked and up came the soon-to-be-named NL Rookie of the Year Albert Pujols. He then hit his first playoff home run to make it 2–0 Cardinals in the top of the first. Then Polanco's sac fly made it 3–0 in the third. The D'Backs would scratch out a run in the eighth, but an error by Miguel Batista gave the Cardinals a commanding 4–1 lead in the ninth. Steve Kline got the save in the bottom of the ninth to even the series.
Game 3, October 12 
|WP: Miguel Batista (1–0) LP: Mike Matthews (0–1) Sv: Byung-Hyun Kim (1)
ARI: Luis Gonzalez (1), Craig Counsell (1)
STL: Jim Edmonds (1), Edgar Rentería (1)
In Game 3, Batista returned to the mound to start. Opposing him would be Darryl Kile. Both pitchers worked their way through each inning and kept it scoreless into the fourth. But Jim Edmonds's two-run homer in the bottom of the fourth gave the Cardinals the lead. Luis Gonzalez responded with a homer off the right field pole to make it a one-run game in the sixth. Then the Diamondbacks came back in dramatic fashion. After Kile allowed a leadoff walk in the top of the seventh, Mike Matthews came on in relief. Greg Colbrunn tied the game with an RBI single with one out. A fielder's choice put two men on for eventual NLCS MVP Craig Counsell. He then hit a three-run home run to right that put the D'Backs ahead by three. However, Rentería would homer to make it a two-run game. But Byung-Hyun Kim closed the door in the ninth. Tragically, this wound up being Kile's final playoff game.
Game 4, October 13 
|WP: Bud Smith (1–0) LP: Albie Lopez (0–1) Sv: Steve Kline (2)
STL: Jim Edmonds (2), Fernando Viña (1)
Albie Lopez looked to close the door on the Cards. Opposing him would be Bud Smith. Smith got into trouble in the top of the first when Steve Finley singled home a run to make it 1–0 Diamondbacks. But J. D. Drew's RBI single tied the game in the bottom half of the inning. Then Jim Edmonds hit the go-ahead home run in the bottom of the second to put the Cardinals up for good. Then Fernando Viña's two-run homer in the third gave the Cardinals insurance. Both bullpens held the other team to nothing for the rest of the game as the series was once again tied.
Game 5, October 14 
|WP: Curt Schilling (2–0) LP: Steve Kline (0–1)
STL: J. D. Drew (1)
ARI: Reggie Sanders (1)
In the clinching Game 5, Matt Morris once again faced Curt Schilling. Both pitchers were on their game, allowing only one run throughout the entire game. Morris was the first to falter in the bottom of the fourth when he gave up a solo home run to Reggie Sanders. Schilling was masterful and was four outs away from winning the series. He was working on a 1–0 four-hit shutout when J. D. Drew tied the game with a solo homer of his own in the eighth. Schilling pitched a complete game and the D'Backs now had to get him the win. A leadoff double by Matt Williams gave the D'Backs a good chance. A sac bunt by Damian Miller put pinch runner Midre Cummings on third. After Colbrunn was walked intentionally, Cummings tried to steal home on the squeeze play attempt and got caught. Colbrunn went to second and Danny Bautista came on to pinch run. Then Tony Womack delivered the series winning single to left field. The Diamondbacks won their first postseason series ever and were now going to their first ever NLCS.
Composite box 
|St. Louis Cardinals||3||1||3||2||0||0||1||1||1||12||29||3|
|Total attendance: 231,321 Average attendance: 46,264|
Series quotes 
It's a little blooper...and that ball drops! Here comes Bautista! And the Diamondbacks...WIN! WOMACK DELIVERS! The Diamondbacks are going to the National League Championship Series against Atlanta! How about that?!
- "2001 NLDS - Atlanta Braves vs. Houston Astros - Game 1". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - Atlanta Braves vs. Houston Astros - Game 2". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - Houston Astros vs. Atlanta Braves - Game 3". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - St. Louis Cardinals vs. Arizona Diamondbacks - Game 1". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - St. Louis Cardinals vs. Arizona Diamondbacks - Game 2". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - Arizona Diamondbacks vs. St. Louis Cardinals - Game 3". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - Arizona Diamondbacks vs. St. Louis Cardinals - Game 4". Retrosheet. Retrieved 2009-09-13.
- "2001 NLDS - St. Louis Cardinals vs. Arizona Diamondbacks - Game 5". Retrosheet. Retrieved 2009-09-13.