The 2001 US Open was held between August 27 – September 9, 2001. It was the final Grand Slam event of 2001.
Marat Safin was unsuccessful in his title defence, being defeated in the semifinals by Pete Sampras in a rematch of the 2000 final, whilst Venus Williams was successful in her title defence, beating her sister Serena in the women's final. 20-year-old Australian Lleyton Hewitt won the men's title, defeating Sampras in the final. It was the second consecutive US Open final defeat for Sampras.
Men's singles 
Lleyton Hewitt def. Pete Sampras, 7–6(7–4), 6–1, 6–1
- It was Hewitt's 8th title of the year, and his 10th overall. It was his 1st career Grand Slam title, and he became the youngest male ever to be ranked number one, at the age of 20.
Women's singles 
Venus Williams def. Serena Williams, 6–2, 6–4
- It was Venus's 6th title of the year, and her 21st overall. It was her 4th career Grand Slam title, and her 2nd US Open title.
Men's doubles 
Wayne Black / Kevin Ullyett def. Donald Johnson / Jared Palmer, 7–6, 2–6, 6–3
Women's doubles 
Lisa Raymond / Rennae Stubbs def. Kimberly Po / Nathalie Tauziat, 6–2, 5–7, 7–5
Mixed doubles 
Rennae Stubbs / Todd Woodbridge def. Lisa Raymond / Leander Paes, 6–4, 5–7, 7–6(9)
Boys' singles 
Gilles Müller def. Yeu-Tzuoo Wang, 7–6(5), 6–2
Girls' singles 
Marion Bartoli def. Svetlana Kuznetsova, 4–6, 6–3, 6–4
Boys' doubles 
Tomáš Berdych / Stéphane Bohli
Girls' doubles 
Galina Fokina / Svetlana Kuznetsova
- ^ Kuznetsova won the 2004 women's singles crown, and reached the 2007 final.
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