Per Big 12 policy, the Big 12 North Champion will be declared the home team this year because the game is scheduled to take place in a home state of a Big 12 South team. Designated "home" teams are 8–3 in Big 12 Championship Games.
The Big 12 North representative in the championship game is the 2007 Missouri Tigers Missouri Tigers football team. The team was coached by Gary Pinkel, who returned in his seventh season with Mizzou, and played their home games at Faurot Field at Memorial Stadium. Quarterback Chase Daniel in his junior year led the Tigers to their first Big 12 Championship Game. The Tigers ended the regular season with a record of 11-1 (7-1, Big 12), with their only loss coming to Oklahoma
Missouri entered the 2007 Big 12 Championship Game ranked #1 and looking for a spot in the BCS National Championship Game. Mizzou took the lead early with a 28 yard Jeff Wolfert field goal. However, on the first play of the 2nd quarter, Oklahoma's Chris Brown rushed for a 3-yard touchdown. Missouri was able to kick another field goal, this time from 18 yards out, to make it a 7-6 Sooner lead. Oklahoma struck back two drives later on a 2-yard touchdown by Chris Brown, his second of the night. Missouri drive down the field on the next drive, scoring on a 4 yard Chase Daniel run and a two-point conversion, tying the game at 14 heading into halftime. The 3rd quarter was all Oklahoma. Consistently putting pressure on Missouri quarterback Chase Daniel, the Sooner defense began to control the game. Allen Patrick scored from 4 yards out and Sam Bradford threw a 5-yard touchdown to Jermaine Gresham to give Oklahoma a 28-14 lead going into the final quarter. Early in the 4th, Wolfert hit his 3rd field goal of the night to bring the score to 28-17. Bradford and Oklahoma scored on the next drive, a 4-yard touchdown pass to Joe Jon Finley giving Oklahoma the 35-17 lead. Sooner kicker Garrett Hartley hit a 26-yard field goal to give Oklahoma a 38-17 lead and finishing off the scoring.