Tory Harrison started the scoring, by rushing 43 yards for a touchdown, to give Southern Miss the first points of the game, 7-0. Damion Fletcher later scored on a e yard touchdown run giving the Eagles a 14-0 lead. With 1:13 left in the half James Denley intercepted an Ohio pass, and returned it 18 yards for another Southern Miss touchdown. The halftime score had Southern Miss up 21-0 over Ohio.
In the third quarter, Damion Fletcher scored on a 9-yard touchdown run to increase the lead to 28-0. Austen Everson threw a 13-yard touchdown pass to Thomas Christy for Ohio, to make the score 28-7. That would end up being the final score of the game.