The 2010–11 Primeira Liga (also known as Liga ZONSagres due to sponsorship reasons) was the 77th season of the Primeira Liga, the top professional league for Portuguese association football clubs. It began on 15 August 2010 and ended on 14 May 2011. A total of 16 teams contested the league, 14 of which already took part in the previous season and two of which were promoted from the Liga de Honra. Benfica were the defending champions but finished runners-up to Porto, who won their 25th league title in the club's first-ever unbeaten season. Porto's forward Hulk was the top scorer with 23 goals.
The two relegated teams were replaced by Liga de Honra champions Beira-Mar and runners-up Portimonense. Beira-Mar returned to the top-level league after five years of absence, and Portimonense made their first appearance in their league since being relegated at the end of the 1989–90 season.
Rules for classification: 1) points; 2) head-to-head points; 3) head-to-head goal difference; 4) head-to-head goals scored; 5) goal difference; 6) number of goals scored. 1The 2010–11 Taça de Portugal competition was won by Champions League-qualified side Porto. Since cup runners-up Vitória de Guimarães secured a place in the European competitions via league position, the spot allocation for the 2011–12 UEFA Europa League effectively reverted to league positions. (C) = Champion; (R) = Relegated; (P) = Promoted; (E) = Eliminated; (O) = Play-off winner; (A) = Advances to a further round.
Only applicable when the season is not finished: (Q) = Qualified to the phase of tournament indicated; (TQ) = Qualified to tournament, but not yet to the particular phase indicated; (RQ) = Qualified to the relegation tournament indicated; (DQ) = Disqualified from tournament.
Head-to-Head: used when head-to-head record is used to rank tied teams.