Region II was decided by a five-team round-robin, with the Kentucky Wanderers edging out both J.B. Marine S.C. and the Croatian Eagles on a goal-differential tiebreaker. The other two teams involved were Vardar East (from Michigan) and Move Makers (Illinois).
Six teams were divided into two groups, with the group winners facing off for Region III's national semifinal slot. The Dallas Premier won their group and then beat the Houston Challengers to move forward. The group runner-ups were the Triad United Aces and the AFC Aces, followed by the Georgia Cougars and the Louisiana Mudbugs