The 2010 Zucchetti Kos Tennis Cup was a professional tennis tournament played on outdoor red clay courts. It was the seventh edition of the tournament which was part of the Tretorn SERIE+ of the 2010 ATP Challenger Tour. It took place in Cordenons, Italy between 26 July and 1 August 2010.
- Rankings are as of July 19, 2010.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Steve Darcis def. Daniel Muñoz-de la Nava, 6–2, 6–4
Robin Haase / Rogier Wassen def. James Cerretani / Adil Shamasdin, 7–6(14), 7–5