The 2011/2012 Armenian Independence Cup was the 21st season of Armenia's football knockout competition. It featured the eight 2012 Premier League teams. The tournament began on 19 November 2011. Mika were the defending champions. The winners entered the first qualifying round of the 2012–13 UEFA Europa League.
All eight Premier League clubs competed in this round. The first legs were played on 19 and 20 November 2011, with the second legs to be competed on 23 and 24 November 2011.
The four winners from the quarterfinals entered this round. The first legs were played on 17 March 2012, with the second legs to be competed on 11 April 2012.