The 2013 Copa Colombia, officially the 2013 Copa Postobón for sponsorship reasons, was the 12th edition of the Copa Colombia, the national cup competition for clubs of DIMAYOR. It began on February 15 and ended on November 8. The tournament comprised a total of 36 teams. The winner earned a berth to the 2014 Copa Sudamericana.
The 36 teams were divided into six groups based on each separate region of Colombia. Each group was played in home-and-away round-robin format. The group winners and runner-ups, along with the four best third-placed teams, advanced to the Round of 16. The matches were played from February 13 to June 5.
Each tie in the knockout phase was played in home-and-away two-legged format. In each tie, the team which had the better overall record up to that stage host the second leg, except in the round of 16 where the group winners automatically hosted the second leg. In case of a tie in aggregate score, neither the away goals rule nor extra time was applied, and the tie was decided by a penalty shoot-out.