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2C-EF, or 4-fluoroethyl-2,5-methoxyphenethylamine, is a lesser-known psychedelic drug and a substituted phenethylamine. 2C-EF was referenced in PiHKAL (Phenethylamines i Have Known And Loved) by Alexander Shulgin when talking about the alpha-methyl analogue DOEF. Alexander Shulgin stated "4-(2-fluoroethyl)phenethylamine, it would be every bit as much a treasure and ally as is 2C-B or 2C-I. In fact, I am sure enough about this prediction that I am willing to name the stuff 2C-EF." Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-EF.