3',4'-Methylenedioxy-α-pyrrolidinopropiophenone

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3',4'-Methylenedioxy-α-pyrrolidinopropiophenone
MDPPP.svg
Systematic (IUPAC) name
(RS)-1-(3,4-methylenedioxyphenyl)-2-(1-pyrrolidinyl)-1-propanone
Clinical data
Legal status Class A (UK)
Routes oral, insufflation, Vaporization, IV, rectal, sublingual
Pharmacokinetic data
Metabolism Hepatic
Excretion Primarily Urine (Renal)
Identifiers
CAS number 24698-57-5
ATC code ?
PubChem CID 6430845
Chemical data
Formula C14H17NO3 
Mol. mass 247.28 g/mol

3',4'-Methylenedioxy-α-pyrrolidinopropiophenone (MDPPP) is a stimulant designer drug. It was sold in Germany in the late 1990s and early 2000s as an ingredient in imitation ecstasy (MDMA) pills.[1] It shares a similar chemical structure with α-PPP and MDPV.[2][3][4]

Metabolism[edit]

MDPPP appears to have a similar metabolic fate as MDPV.[4]

See also[edit]

References[edit]

  1. ^ Springer, D.; Fritschi, G.; Maurer, H. H. (2003). "Metabolism and toxicological detection of the new designer drug 3′,4′-methylenedioxy-α-pyrrolidinopropiophenone studied in urine using gas chromatography–mass spectrometry". Journal of Chromatography B 793 (2): 377. doi:10.1016/S1570-0232(03)00350-7.  edit
  2. ^ Maurer, HH; Kraemer, T; Springer, D; Staack, RF (2004). "Chemistry, pharmacology, toxicology, and hepatic metabolism of designer drugs of the amphetamine (ecstasy), piperazine, and pyrrolidinophenone types: a synopsis". Therapeutic drug monitoring 26 (2): 127–31. doi:10.1097/00007691-200404000-00007. PMID 15228152. 
  3. ^ Staack, RF; Maurer, HH (2005). "Metabolism of designer drugs of abuse". Current drug metabolism 6 (3): 259–74. doi:10.2174/1389200054021825. PMID 15975043. 
  4. ^ a b Springer, D; Staack, RF; Paul, LD; Kraemer, T; Maurer, HH (2005). "Identification of cytochrome P450 enzymes involved in the metabolism of 3',4'-methylenedioxy-alpha-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes". Xenobiotica 35 (3): 227–37. doi:10.1080/00498250400028239. PMID 16019948.