3,4-Dihydroxystyrene

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3,4-Dihydroxystyrene
3,4-Dihydroxystyrene.png
3,4-dihydroxystyrene-3D-balls.png
Systematic (IUPAC) name
4-vinylbenzene-1,2-diol
Clinical data
Legal status
  • Uncontrolled
Identifiers
CAS number 6053-02-7 N
ATC code None
PubChem CID 151398
ChemSpider 133430 YesY
KEGG C06224 YesY
Chemical data
Formula C8H8O2 
Mol. mass 136.15 g/mol
 N (what is this?)  (verify)

3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.

See also[edit]

References[edit]

  1. ^ Koizumi S, Matsushima Y, Nagatsu T, Iinuma H, Takeuchi T, Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica Et Biophysica Acta 789 (2): 111–8. doi:10.1016/0167-4838(84)90194-8. PMID 6148105.