3,4-Methylenedioxyphenylpropan-2-one

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3,4-Methylenedioxyphenylpropan-2-one
MDP2P.svg
Names
IUPAC name
3,4-methylenedioxyphenylpropan-2-one[1]
Other names
3,4-methylenedioxyphenyl-2-propanone, 1-(1,3-benzodioxol-5-yl)propan-2-one, piperonyl methyl ketone
Identifiers
Abbreviations MDP2P, PMK
ChemSpider 70776 YesY
Jmol-3D images Image
PubChem 78407
Properties
C10H10O3
Molar mass 178.185 g/mol
Appearance Yellowish green liquid
Density 1.211 g/cm3
Boiling point 290 °C (554 °F; 563 K)
Pharmacology
Legal status
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

3,4-Methylenedioxyphenylpropan-2-one[1] or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. It is commonly synthesized from either safrole ((which, for comparison, is 3-[3,4-(methylenedioxy)phenyl]-2-propene) or its isomer isosafrole via oxidation using the Wacker oxidation or peroxyacid oxidation methods. MDP2P is unstable at room temperature and must be kept in the freezer in order to be preserved properly.

MDP2P is a precursor in the chemical synthesis of the methylenedioxyphenethylamine (MDxx) class of compounds, the classic example of which is 3,4-methylenedioxy-N-methylamphetamine (MDMA), and is also an intermediate between the MDxx family and their slightly more distant precursor safrole or isosafrole. On account of its relation to the MDxx chemical class, MDP2P, as well as safrole and isosafrole, are in the United States (U.S.) Drug Enforcement Administration (DEA) List I of Chemicals of the Controlled Substances Act (CSA) via the Chemical Diversion and Trafficking Act (CDTA). It is also considered a category 1 precursor in the European Union.

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