3,4-dihydroxyphthalate decarboxylase

3,4-dihydroxyphthalate decarboxylase
Identifiers
EC number	4.1.1.69
CAS number	83137-76-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a 3,4-dihydroxyphthalate decarboxylase (EC 4.1.1.69) is an enzyme that catalyzes the chemical reaction

3,4-dihydroxyphthalate $\rightleftharpoons$ 3,4-dihydroxybenzoate + CO₂

Hence, this enzyme has one substrate, 3,4-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming). This enzyme is also called 3,4-dihydroxyphthalate carboxy-lyase.

References

• Eaton RW, Ribbons DW (1982). "Metabolism of dibutylphthalate and phthalate by Micrococcus sp. strain 12B". J. Bacteriol. 151 (1): 48–57. PMC 220188. PMID 7085570. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=220188.