3-Fluoroamphetamine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
3-Fluoroamphetamine
3-fluoroamphetamine.svg
Ball-and-stick model of the 3-fluoroamphetamine molecule
Systematic (IUPAC) name
(RS)-1-(3-Fluorophenyl)propan-2-amine
Clinical data
  • Unscheduled
Oral
Identifiers
1626-71-7 N
PubChem CID 121501
ChemSpider 108417 YesY
Chemical data
Formula C9H12FN
153.196 g/mol
 N (what is this?)  (verify)

3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and noradrenaline release over serotonin.[1] It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.[2]

See also[edit]

References[edit]

  1. ^ Negus, SS; Mello, NK; Blough, BE; Baumann, MH; Rothman, RB (2007). "Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys". The Journal of Pharmacology and Experimental Therapeutics 320 (2): 627–36. doi:10.1124/jpet.106.107383. PMID 17071819. 
  2. ^ Wee, S; Anderson, KG; Baumann, MH; Rothman, RB; Blough, BE; Woolverton, WL (2005). "Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs". The Journal of Pharmacology and Experimental Therapeutics 313 (2): 848–54. doi:10.1124/jpet.104.080101. PMID 15677348.