3-Fluoroethamphetamine

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3-Fluoroethamphetamine
3-Fluoroethamphetamine.png
Systematic (IUPAC) name
1-(3-fluorophenyl)-2-ethylaminopropane
Clinical data
Legal status ?
Identifiers
CAS number  YesY
ATC code None
Chemical data
Formula C11H16FN 
Mol. mass 181.249 g/mol
 YesY (what is this?)  (verify)

3-Fluoroethamphetamine (3-FEA) is a stimulant drug which acts as a releaser of the monoamine neurotransmitters noradrenaline, dopamine and serotonin. Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.[1][2][3][4]

See also[edit]

References[edit]

  1. ^ Tessel RE, Woods JH. Structural relationship between meta-substituted N-ethylamphetamines and self-administration in rhesus monkeys. Pharmacologist 1974;16:142.
  2. ^ Tessel RE, Woods JH, Counsell RE, Lu M (February 1975). "Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice". The Journal of Pharmacology and Experimental Therapeutics 192 (2): 310–8. PMID 1117418. 
  3. ^ Tessel RE, Rutledge CO (May 1976). "Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives". The Journal of Pharmacology and Experimental Therapeutics 197 (2): 253–62. PMID 1271279. 
  4. ^ Tessel RE, Woods JH (May 1978). "meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships". The Journal of Pharmacology and Experimental Therapeutics 205 (2): 274–81. PMID 417172.