3H 7O 7P
Molar mass 186.06 g·mol
Except where noted otherwise, data is given for materials in their
(at 25 °C (77 °F), 100 kPa)
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3-Phosphoglyceric acid ( 3PG), or glycerate 3-phosphate ( GP), is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, 3-Phosphoglycerate is the product of the spontaneous split of an unstable 6-carbon intermediate formed by CO 2 fixation. Thus, two 3-phosphoglycerate molecules are produced for each molecule of CO 2 fixed.
Glycolysis [ edit ]
Compound C00236 at KEGG Pathway Database. Enzyme 220.127.116.11 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 18.104.22.168 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.
Click on genes, proteins and metabolites below to link to respective articles. [§ 1 ]
Glycolysis and Gluconeogenesis
Calvin cycle [ edit ]
light-independent reactions (also known as the Calvin cycle), two 3-phosphoglycerate molecules are synthesized, one of which continues through the Calvin cycle to be regenerated to Rubisco and the other is reduced to form one molecule of glyceraldehyde 3-phosphate (G3P). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule that is easily reduced.
Amino acid synthesis [ edit ]
Glycerate 3-phosphate is also a precursor for
serine, which, in turn, can create cysteine and glycine through the homocysteine cycle.
See also [ edit ]
PAMs: Alcohols (e.g., brometone, chlorobutanol (chloretone), ethanol, , tert-butanol (2M2P) tribromoethanol, trichloroethanol, trifluoroethanol)
Barbiturates (e.g., pentobarbital, sodium thiopental)
Dihydropyridines (e.g., nicardipine)
Ginseng constituents (e.g., ginsenosides (e.g., ginsenoside-Rf))
Glutamic acid (glutamate)
Neuroactive steroids (e.g., alfaxolone, pregnenolone (eltanolone), pregnenolone acetate, minaxolone, Org 20599)
Tropeines (e.g., atropine, bemesetron, cocaine, LY-278584, tropisetron, zatosetron)
Volatiles/ gases (e.g., chloral hydrate, chloroform, desflurane, diethyl ether (ether), enflurane, halothane, isoflurane, methoxyflurane, sevoflurane, toluene, trichloroethane (methyl chloroform), trichloroethylene)
Endocannabinoids (e.g., 2-AG, anandamide (AEA))
Quinolines (e.g., 4-hydroxyquinoline, 4-hydroxyquinoline-3-carboxylic acid, 5,7-CIQA, 7-CIQ, 7-TFQ, 7-TFQA)
Benzodiazepines (e.g., bromazepam, clonazepam, diazepam, flunitrazepam, flurazepam)
Dihydropyridines (e.g., nicardipine, nifedipine, nitrendipine)
Ginkgo constituents (e.g., bilobalide, ginkgolides (e.g., ginkgolide A, ginkgolide B, ginkgolide C, ginkgolide J, ginkgolide M))
Neuroactive steroids (e.g., 3α-androsterone sulfate, 3β-androsterone sulfate, deoxycorticosterone, DHEA sulfate, pregnenolone sulfate, progesterone)
Opioids (e.g., codeine, dextromethorphan, dextrorphan, levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine)
Picrotoxin (i.e., picrotin and picrotoxinin)
Tropeines (e.g., bemesetron, LY-278584, tropisetron, zatosetron)