3-hydroxyanthranilate oxidase

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3-hydroxyanthranilate oxidase
Identifiers
EC number 1.10.3.5
CAS number 37256-53-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 3-hydroxyanthranilate oxidase (EC 1.10.3.5) is an enzyme that catalyzes the chemical reaction

3-hydroxyanthranilate + O2 \rightleftharpoons 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2

Thus, the two substrates of this enzyme are 3-hydroxyanthranilate and O2, whereas its two products are 6-imino-5-oxocyclohexa-1,3-dienecarboxylate and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen oxidoreductase. This enzyme is also called 3-hydroxyanthranilic acid oxidase.

References[edit]

  • Morgan LR Jr, Weimorts DM, Aubert CC (1965). "Oxidation Of 3-hydroxyanthranilic acid by a soluble liver fraction from poikilothermic vertebrates". Biochim. Biophys. Acta. 100: 393–402. PMID 14347936.