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Systematic (IUPAC) name
Clinical data
486459-03-4 YesY
PubChem 1807 CID 10421832 1807
ChemSpider 8597261 YesY
Chemical data
Formula C10H12BrNO
242.11 g/mol
 YesY (what is this?)  (verify)

4-Bromomethcathinone (4-BMC, Brephedrone) is a psychoactive drug and research chemical of the phenethylamine, amphetamine, and cathinone chemical classes. It acts as a serotonin and norepinephrine reuptake inhibitor,[1][2] but acts more like an antidepressant than a stimulant.[3] It is currently unclear whether the 4-halogenated cathinones share the selective serotonergic neurotoxicity of their corresponding amphetamines.

See also[edit]


  1. ^ Foley, K. F.; Cozzi, N. V. (1999). "Bromine substitution at the ring 3- or 4-position of methcathinone enhances potency at serotonin uptake transporters". Society for Neuroscience Abstracts 25 (1–2): 1701. 678.17. 
  2. ^ Foley, K. F.; Cozzi, N. V. (2002). "Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N-ethylmaleimide and protection by substrate analogs". Naunyn-Schmiedeberg's Archives of Pharmacology 365 (6): 457–461. doi:10.1007/s00210-002-0532-3. PMID 12070759. 
  3. ^ Foley, K. F.; Cozzi, N. V. (2003). "Novel aminopropiophenones as potential antidepressants" (PDF). Drug Development Research 60 (4): 252–260. doi:10.1002/ddr.10297.