4-HO-DSBT

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4-HO-DSBT
4-HO-DSBT.png
Systematic (IUPAC) name
3-[2-[di(butan-2-yl)amino]ethyl]-1H-indol-4-ol
Clinical data
Legal status ?
Identifiers
CAS number  N
ATC code ?
PubChem CID 21786580
Chemical data
Formula C18H28N2O 
Mol. mass 288.43 g/mol

4-HO-DSBT (4-hydroxy-N,N-di-sec-butyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It was first made by Alexander Shulgin and is mentioned in his book TiHKAL, but was never tested by him.[1] However it has subsequently been tested in vitro and unlike the n-butyl and isobutyl isomers which are much weaker, the s-butyl derivative retains reasonable potency, with a similar 5-HT2A receptor affinity to MiPT but better selectivity over the 5-HT1A and 5-HT2B subtypes.[2]

See also[edit]

References[edit]

  1. ^ 4-HO-DBT TiHKAL entry
  2. ^ McKenna, D. J.; Repke, D. B.; Lo, L.; Peroutka, S. J. (1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.  edit