|Millennium:||1st millennium BC|
|Centuries:||6th century BC – 5th century BC – 4th century BC|
|Decades:||510s BC 500s BC 490s BC – 480s BC – 470s BC 460s BC 450s BC|
|Years:||483 BC 482 BC 481 BC – 480 BC – 479 BC 478 BC 477 BC|
|480 BC by topic|
|Gregorian calendar||480 BC|
|Ab urbe condita||274|
|Bahá'í calendar||−2323 – −2322|
|English Regnal year||N/A|
|Chinese calendar||庚申年 (Metal Monkey)
2217 or 2157
— to —
辛酉年 (Metal Rooster)
2218 or 2158
|Coptic calendar||−763 – −762|
|Ethiopian calendar||−487 – −486|
|- Vikram Samvat||−423 – −422|
|- Shaka Samvat||N/A|
|- Kali Yuga||2622–2623|
|Igbo calendar||−1479 – −1478|
|Iranian calendar||1101 BP – 1100 BP|
|Islamic calendar||1135 BH – 1134 BH|
|Minguo calendar||2391 before ROC
|Thai solar calendar||64|
|Wikimedia Commons has media related to 480 BC.|
Year 480 BCE was a year of the pre-Julian Roman calendar. At the time, it was known as the Year of the Consulship of Vibulanus and Cincinnatus (or, less frequently, year 274 Ab urbe condita). The denomination 480 BCE for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- May – King Xerxes I of Persia marches from Sardis and onto Thrace and Macedonia.
- The Greek congress decides to send a force of 10,000 Greeks, including hoplites and cavalry, to the Vale of Tempe, through which they believe the Persian army will pass. The force includes Lacedaemonians led by Euanetos and Athenians under Themistocles. Warned by Alexander I of Macedon that the vale can be bypassed elsewhere and that the army of Xerxes is overwhelming, the Greeks decide not to try to hold there and vacate the vale.
- August 11 – The Battle of Thermopylae ends in victory for the Persians under Xerxes. His army engulfs a force of 300 Spartans and 700 Thespiae under the Spartan King, Leonidas I. The Greeks under Leonidas resist the advance through Thermopylae of Xerxes' vast army. For two days Leonidas and his troops withstand the Persian attacks; he then orders most of his troops to retreat, and he and his 300-member royal guard fight to the last man.
- A member of the Agiad royal family, and the son of King Cleombrotus and nephew of King Leonidas, Pausanias becomes regent for Leonidas' son, Pleistarchus, after Leonidas I is killed at Thermopylae.
- Phocis and the coasts of Euboea are devastated by the Persians. Thebes and most of Boeotia join Xerxes.
- King Alexander I of Macedon is obliged to accompany Xerxes in a campaign through Greece, though he secretly aids the Greek allies. With Xerxes' apparent acquiescence, Alexander seizes the Greek colony of Pydna and advances his frontiers eastward to the Strymon, taking in Crestonia and Bisaltia, along with the rich silver deposits of Mount Dysorus.
- The Athenian soldier and statesman, Aristides, as well as the former Athenian archon Xanthippus, return from banishment in Aegina to serve under Themistocles against the Persians.
- August – The Persians achieve a naval victory over the Greeks in an engagement fought near Artemisium, a promontory on the north coast of Euboea. The Greek fleet holds its own against the Persians in three days of fighting but withdraws southward when news comes of the defeat at Thermopylae.
- Breaking through the pass at Thermopylae from Macedonia into Greece, the Persians occupy Attica.
- September 21 – The Persians sack Athens, whose citizens flee to Salamis and then Peloponnesus.
- September 22 – The Battle of Salamis brings victory to the Greeks, whose Athenian general Themistocles lures the Persians into the Bay of Salamis, between the Athenian port-city of Piraeus and the island of Salamis. The Greek triremes then attack furiously, ramming or sinking many Persian vessels and boarding others. The Greeks sink about 200 Persian vessels while losing only about 40 of their own. The rest of the Persian fleet is scattered, and as a result Xerxes has to postpone his planned land offensives for a year, a delay that gives the Greek city-states time to unite against him.
- An eclipse of the sun discourages the Greek army from following up the victory of Salamis. Xerxes returns to Persia leaving behind an army under Mardonius, which winters in Thessaly.
- Xerxes encourages the Carthaginians to attack the Greeks in Sicily. Under the Carthaginian military leader, Hamilcar, Carthage sends across a large army.
- The Greek city of Himera in Sicily, in its quarrel with Akragas, enlists Carthaginian support. With the help of Gelo, the tyrant of Syracusae, and Theron of Akragas, the Carthaginians are defeated in the Battle of Himera. After the defeat, Hamilcar kills himself.
- The Imperial treasury at the Persepolis Palace is completed after a building time of thirty years.
- The archaic period of sculpture ends in Greece and is succeeded by the Severe (Early Classical) period (approximate date).
- A sculpture of a Dying warrior is made in the left corner of the east pediment of the Temple of Aphaea in Aegina (approximate date). Today, it is preserved at the Staatliche Antikensammlungen und Glyptothek in Munich, Germany.
- The sculpture of a Kritios Boy is made on Acropolis, Athens (approximate date). It is now preserved in the Acropolis Museum in Athens.
- Work begins on the detail Musicians and Dancers on a wall painting in the Tomb of the Lionesses in Tarquinia. It is finished some ten years later.
- Euripides, Greek playwright (d. 406 BCE)
- Antiphon, Attic orator (d. 411 BCE)
- Philolaus, Greek mathematician and philosopher (d. c. 405 BCE)
- August 11 – Leonidas I, Agiad King of Sparta (died at Thermopylae)
- Xenophanes, Greek philosopher (b. 570 BC)
- Hamilcar, Carthaginian general (suicide after his defeat in the Battle of Himera)
- Zhong You (Zilu), a prominent disciple of Confucius (b. 542 BC)