5'-Methoxyhydnocarpin

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5'-Methoxyhydnocarpin
5'-methoxyhydnocarpin.png
Names
IUPAC name
5,7-Dihydroxy-2-[(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydro-1,4-benzodioxin-7-yl]chromen-4-one
Other names
5′-MHC
Identifiers
ChemSpider 4445172
Jmol-3D images Image
KEGG C11162
PubChem 5281879
Properties
C26H22O10
Molar mass 494.45 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

5'-Methoxyhydnocarpin (5′-MHC) is a chemical compound that has been isolated from Berberis[1] and Hydnocarpus wightianus.[2]

5′-MHC potentiates the antimicrobial effect of berberine in vitro.[1]

References[edit]

  1. ^ a b Stermitz, F. R.; Lorenz, P; Tawara, J. N.; Zenewicz, L. A.; Lewis, K. (February 15, 2000). "Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor". Proceedings of the National Academy of Sciences (National Academy of Sciences) 97 (4): 1433–1437. Bibcode:2000PNAS...97.1433S. doi:10.1073/pnas.030540597. ISSN 1091-6490. PMC 26451. PMID 10677479. 
  2. ^ Williams, Cheryll (2013). Medicinal Plants in Australia Volume 4: An Antipodean Apothecary. Rosenberg Publishing. p. 171. ISBN 9781925078084.