5'-nucleotidase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
5'-nucleotidase
Identifiers
EC number 3.1.3.5
CAS number 9027-73-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

5'-nucleotidase (EC 3.1.3.5, uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase) is an enzyme with system name 5'-ribonucleotide phosphohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction

a 5'-ribonucleotide + H2O \rightleftharpoons a ribonucleoside + phosphate

This enzyme has a wide specificity for 5'-nucleotides.

References[edit]

  1. ^ Gulland, J.M. and Jackson, E.M. (1938). "5-Nucleotidase". Biochem. J. 32: 597–601. PMID 16746659. 
  2. ^ Heppel, L.A. and Hilmoe, R.J. (1951). "Purification and properties of 5-nucleotidase". J. Biol. Chem. 188: 665–676. PMID 14824154. 
  3. ^ Segal, H.L. and Brenner, B.M. (1960). "5′-Nucleotidase of rat liver microsomes". J. Biol. Chem. 235: 471–474. PMID 14444527. 

External links[edit]