|Jmol-3D images||Image 1
|Melting point||98-99 °C|
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a brominated indole alkaloid found in certain marine invertebrates. It is the 5-bromo analogue of DMT, a psychedelic found in many plants and animals. Other naturally occurring 5-substituted analogues of DMT include bufotenin and 5-MeO-DMT, both of which, like DMT, are psychoactive and found in plants and animals. Animal studies on 5-bromo-DMT showed it to produce effects suggestive of sedative and antidepressant activity.
This compound is soluble in ethanol and methanol. It has been found in Verongula rigida (0.00142% dry wt.) along with 5,6-diBr-DMT (0.35% dry wt.) and seven other alkaloids. 5-Br-DMT caused significant reduction of locomotor activity in the rodent FST model (suggested to indicate a potential sedative action). It did not show any antidepressant activity in either test. 
- Djura, Peter et al. (1980). "Some Metabolites of the Marine Sponges Smenospongia aurea and Smenospongia (= Polyfibrospongia) echina". Journal of Organic Chemistry 45 (8): 1435–1441. doi:10.1021/jo01296a019.
- Kochanowska AJ, Rao KV, Childress S, El-Alfy A, Matsumoto RR, Kelly M, Stewart GS, Sufka KJ, Hamann MT (February 2008). "Secondary metabolites from three Florida sponges with antidepressant activity". Journal of Natural Products 71 (2): 186–9. doi:10.1021/np070371u. PMID 18217716.
- Morris H. Wallach J. (March 2013). "SEA DMT: God Molecule or Barnacle Repellant". Vice Magazine. Retrieved 2013-03-27.
- Kochanowska et al. 2008
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