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|Molar mass||267.16 g·mol−1|
|Melting point||98 to 99 °C (208 to 210 °F; 371 to 372 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is: / ?)(|
5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a brominated indole alkaloid found in certain[specify] marine invertebrates. It is the 5-bromo derivative of DMT, a psychedelic found in many plants and animals. Animal studies on 5-bromo-DMT showed that it produces effects suggestive of sedative and antidepressant activity.
This compound is soluble in ethanol and methanol. It has been found in Verongula rigida (0.00142% dry wt.) along with 5,6-diBr-DMT (0.35% dry wt.) and seven other alkaloids. 5-Br-DMT caused significant reduction of locomotor activity in the rodent FST model (suggested to indicate a potential sedative action). It did not show any antidepressant activity in either test.
The synthesis and description on the subjective effects of 5-Br-DMT ingestion in humans has been reported. Melting point of the freebase from hexanes is reported to be 99-102.3°C The compound was reported to be psychoactive at 20-50 mg via vaporization with mild psychedelic-like activity. This is the first report of human ingestion.
- Djura, Peter et al. (1980). "Some Metabolites of the Marine Sponges Smenospongia aurea and Smenospongia (= Polyfibrospongia) echina". Journal of Organic Chemistry 45 (8): 1435–1441. doi:10.1021/jo01296a019.
- Kochanowska AJ, Rao KV, Childress S, El-Alfy A, Matsumoto RR, Kelly M, Stewart GS, Sufka KJ, Hamann MT (February 2008). "Secondary metabolites from three Florida sponges with antidepressant activity". Journal of Natural Products 71 (2): 186–9. doi:10.1021/np070371u. PMID 18217716.
- Morris, H, Wallach J. SEA DMT GOD MOLECULE OR BARNACLE REPELLENT? VICE. 2013. http://www.vice.com/read/sea-dmt-000481-v20n3